Koei Tecmo and Gust will release Atelier Resleriana: The Red Alchemist and the White Guardian on September 26, 2025, for Nintendo Switch, PlayStation 5, and PC. Pre-orders are available, with a digital early purchase bonus for those who order by October 9, 2025. The game follows Rias Eidreise and Slade Clauslyter in the region of Hallfein, where they investigate the disappearance of its inhabitants. Rias is an alchemist, and Slade uses a Geist Core to navigate alternate dimensions. The early purchase bonus includes two costumes and an Adventuring Charm Set. This game is connected to Atelier Resleriana: Forgotten Alchemy and the Polar Night Liberator, which was discontinued in March 2025. The game will also be available on PlayStation 4 in Japan.