In a bio-research lab in Dire Marsh, graffiti reading “THAKGODITSYOU. THANKODDITSYOU. THAANKGODITSYOU. THANKOOOITSYOU.” has become notable, appearing in Marathon's promotional art. The modern version of Marathon emphasizes information gathering, similar to its 1994 predecessor, which featured an Alien-inspired motion tracker and a fusion pistol with a distinctive firing mechanism. The game explores themes of disconnection between body and consciousness, with options available in the Aleph One port on Steam to alleviate motion sickness. The lore includes concepts of runners and their shells, highlighting the struggle against disconnection and the pursuit of freedom, as articulated by the character Durandal.