The Dell Latitude 5420 is powered by an Intel Core i5 11th Generation processor (1135G7), Intel Iris Xe graphics, 8GB of RAM, and a 256GB SSD. The Lenovo ThinkBook 15 features an AMD Ryzen 3 5300U processor, 8GB of RAM, and a 512GB SSD. The Dell Latitude 5420 runs on Windows 10, while the Lenovo ThinkBook 15 comes with Windows 11. The Dell Latitude 5420 is positioned as a premium option, while the Lenovo ThinkBook 15 is a more budget-friendly alternative.